The fact that flashing light on a photoreceptor, whether a rod or a cone, results in membrane hyperpolarization rather than depolarization, may be even more startling.
A graded potential is a slight departure from the RMP that does not affect the membrane. less polarized or more polarized (inside more negative) (inside less negative) It is known as when the response causes the membrane to become MORE polarized. hyperpolarizing potential in grades. Acetylcholine is released when an action potential is conveyed to the axon terminal, where depolarization causes voltage-gated calcium channels to open and enable an influx of calcium, which then permits the release of acetylcholine-containing vesicles into the synaptic cleft.
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