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What is the effect of a nucleotide-pair substitution that results in a nonsense mutation in a gene?.

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Using the theories of mutation, we got that  the effect of a nucleotide-pair substitution that results in a nonsense mutation in a gene is -

  • It introduces a premature stop codon into the mRNA.

A nonsense mutation is the substitution of the single base pair that leads to the appearance of the stop codon where previously there was a codon specifying an amino acid.

A substitution mutation is when one nucleotide is actually swapped out for another. These types of the mutations are the least dangerous of all the DNA mutations.

Hence, the  effect of a nucleotide-pair substitution that results in a nonsense mutation in a gene is that -It introduces a premature stop codon into the mRNA.

To know more about mutation, visit here:

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(Complete question) is:

What is the effect of a nucleotide-pair substitution that results in a nonsense mutation in a gene?

A. It has no effect on the amino acid sequence of  encoded protein.

B. It introduces a premature stop codon into the mRNA.

C. It alters the reading frame of the mRNA.

D. It changes an amino acid in the encoded protein.

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