Of the four main categories of biotransformation reactions, Conjugation reaction will be considered a phase ii reaction.
A hazardous intermediate or a benign metabolite generated in phase I that needs additional transformation to enhance its polarity gets added hydrophilic groups in phase II reactions. These include glucuronidation, acetylation, sulfation, as well as conjugation processes.
Hydroxylation in conjunction by reduction, oxidation, side chain degradation, and rupture of C-C bonds in conjunction mostly with side chain oxidation.
Therefore, Of the four main categories of biotransformation reactions, Conjugation reaction will be considered a phase ii reaction.
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