Professor Loy tells his class that Lashley failed to find the engram because he didn't fully understand the principles of LTP.
Engram is a hypothetical change in neural tissue postulated in order to account for the persistence of memory. This term represents the physical processes and changes that constitute memory in the brain. Experiments on rodents have revealed that engrams exist as multiscale networks of neurons.
In neuroscience, Long-term potentiation (LTP) is a persistent strengthening of synapses based on recent patterns of activity. These patterns of synaptic activity produce a long-lasting increase in signal transmission between the two neurons. It is a process by which synaptic connections between neurons become stronger with frequent activation.
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