The presence of many microvilli creates a brush boundary in the proximal convoluted tubule region of the renal tubule.
Microvilli are minuscule cellular membrane protrusions that have a variety of functions, including as mechanotransduction, secretion, absorption, and cellular adhesion. They improve the diffusion surface area while minimizing volume expansion. The cytoplasm and microfilaments are enclosed by the plasma membrane that protects microvilli.
The microvilli are extensions of cells, although they only have a few or no cellular organelles. Each microvillus contains a dense bundle of cross-linked actin filaments as its structural core. Between 20 and 30 tightly packed actin filaments make up the core of the microvilli, which are cross-linked by the bundling proteins Fimbrin (or plastin-1), Villin, and Espin.
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