The inheritance pattern of thalassemia disease can be established by observing the genotype of an individual and/or estimating frequency by a pedigree.
Thalassemia is a blood disorder/disease that is inherited as a recessive condition, which means that both alleles must be present to show the disease state.
In a monogenic disease, the expression of dominant alleles can mask the presence of dominant alleles in carrier individuals, but they are evidenced by a pedigree tree.
In conclusion, the inheritance pattern of thalassemia disease can be established by observing the genotype of an individual and/or estimating frequency by a pedigree.
Learn more about recessive diseases here:
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