Buprenorphine's affinity (the strength with which a drug binds to its receptor) for the mu opioid receptor is very high .
The μ receptors are the main functioning target of morphine and drugs like it. The opioid receptors are present in the nervous system, where they are placed in the outer membrane of nerve cells (i.e., neurons).
The opioid receptors are one of the most successful treatments for severe pain.
It is so as, it has high affinity binding to the mu opioid receptors and slow severance kinetics/low intrinsic activity. It is contemplated as a partial agonist with very high binding affinity for the μ-opioid receptor.
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