The interaction of two or more drugs at the same receptor site in which one blocks the action of the other is option(a) i.e, Antagonism.
Antagonism is a reaction that occurs when two or more medications taken together have divergent physiological effects. The effects of one or more of the medications may be obstructed or diminished by drug antagonistic effects. A substance known as an antagonist binds to opioid receptors but does not cause them to become active, blocking the effects of opioids. All-agonist opioids are blocked by antagonists, which have no opiate action. Naloxone and naltrexone are a couple of examples.
Providing the antagonist is administered at the proper dosage, competitive antagonism is the antagonism that prevents or reverses the actions of an agonist. It is entirely possible to overcome the conflict. Noncompetitive antagonism occurs when the antagonist eliminates the receptor or its response potential from the system; this can be done by preventing the agonist from having its desired impact at a receptor site, by irreversible alteration.
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