Prokaryotic promoters have a UP element, which is 40–60 bases upstream of the transcription start site and improves RNA polymerase interaction.
The promoter in prokaryotes is made up of two brief sequences that are located at -10 and -35 upstream from the transcription start point. The Pribnow box, also known as the -10 element, is a sequence that typically consists of the six nucleotides TATAAT.
RNA polymerase (RNAP) interacts with DNA sequences upstream of a promoter to form UP elements (upstream elements), which can change how RNAP binds to DNA and effect transcription. Uncertainty exists regarding the specifics of how UP elements and binding affinities affect transcriptional strength.
So lastly we can say that The UP element, which is found in prokaryotic promoters and is located 40–60 bases upstream of the transcription start point, enhances RNA polymerase interaction.
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