Devices or technologies that can kill and bring substantial harm to a large number of humans or cause great damage to human-made structures, natural structures, or the biosphere are known as: Weapons of mass destruction.
A weapon of mass devastation is a nuclear, radiological, chemical, biological, or another device that is intended to harm a large number of people.
The Department of Homeland Security operates every day to prevent terrorists and other danger actors from using these weapons to harm Americans.
Tsar Bomba
Russia's Tsar Bomba: World's strong nuclear weapon of mass destruction. The Tsar Bomba burst about 4 km above the ground and reportedly created a mushroom cloud 60 km high.
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