Innate defense is her body's first response for Marsha gets a splinter in her finger. as the splinter penetrates her skin, potentially introducing microbes into her tissues.
Innate or nonspecific defenses prevent or limit microorganisms and other environmental hazards from approaching, entering, or spreading. These defenses are often able to prevent infection by destroy-Ing pathogens, without needing the help of any other defenses. Sometimes, however, the adaptive immune system is needed to assist the nonspecific defenses. Nonspecific defenses are the first line of defense and include intact skin and mucosae. When pathogens penetrate the skin or mucosae, the second line of defense is activated. This relies on internal defenses, including antimicrobial proteins and phagocytes. Inflammation is the most important process in the second line of defense. The nonspecific defenses are classified as mechanical barriers, which cover body surfaces, and chemical substances, which are involved with invading pathogens.
If innate defenses are overwhelmed and virus replication continues unabated, then the second-line defenses are mobilized to ensure host survival. These comprise the adaptive immune response – antibodies and immune cells.
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