Dapsone is the drug identified as an antitubercular agent.
Sulfone Dapsone is a member of the class of drugs known as anti-infectives. Leprosy (Hansen's disease) and the skin condition dermatitis herpetiformis are both conditions that are treated with dapsone. Dapsone may be administered along with one or more additional medications while treating leprosy.
Antitubercular agents function by preventing the development of the TB-causing bacteria (Mycobacterium tuberculosis). They work by reversibly blocking DNA-dependent RNA polymerase, which subsequently prevents the production and transcription of bacterial proteins. In vitro, dapsone shows action against Mycobacterium avium complex (MAC) and Mycobacterium tuberculosis. We investigated the prevalence of mycobacterial illnesses within a randomized prospective trial of prophylaxis for toxoplasmosis and Pneumocystis carinii pneumonia.
Dapsone's most frequent adverse effects are nausea, vomiting, headaches, dizziness or a spinning sensation, impaired vision, and ringing in the ears, issues with sleep (insomnia).
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