If a drug is given at intervals that are the same as its half-life it will take about 5 half-lives to reach steady state.
What is the half-life of a drug?
- The period of time it takes for a drug's active ingredient to decrease by half in your body is known as the half-life.
- This is dependent on how the body breaks down and eliminates the substance.
- It could last a few hours, a few days, or even a few weeks. For any particular drug, understanding the idea of half-life is helpful in calculating steady-state concentrations and excretion rates.
- Although different medications have varied half-lives, they always adhere to the same principle: 50% of the initial drug dose is eliminated from the body after one half-life.
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