In prokaryotes, replication usually begins at a specific place on the chromosome called the origin of replication.
An origin of replication is a DNA sequence where chromosomal, plasmid, or viral replication starts. A single origin is adequate for tiny DNAs, such as bacterial plasmids and small viruses. Larger DNAs have multiple origins, and DNA replication is started at each one because it would take too long to replicate the entire DNA mass if replication had to start at just one origin.
Any foreign DNA is connected to the sequence at the origin of replication, which is where replication begins. The host cells are where the replication takes place. The number of connected DNA copies is likewise managed by this new sequence.
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