The inability of muscle cells to relax due to high-frequency stimulation is called tetanus.
A tetanic contraction is a sustained muscle contraction induced when the motor nerve that innervates a skeletal muscle produces action potentials at a very high rate. During this state, the motor neuron stimulates the motor units to their maximum rate and remains that way for some time. This occurs when a muscle's motor unit is stimulated by multiple impulses at a high frequency. Each stimulus causes a twitch. If stimuli are delivered slowly enough, the tension in the muscle will relax between successive twitches. If stimuli are delivered at a high frequency, the twitches will overlap, resulting in tetanic contraction.
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