A drop in the ratio of sodium bicarbonate to carbonic acid because of untreated diabetes can be called Diabetic acidosis
In DKA, a lower pH will usually be associated with a decrease in bicarbonate to 15 mmol/L or less, although a milder form of DKA may present with a bicarbonate level between 15 and 18 mmol/L. Less severe DKA is always accompanied by moderate to large amounts of ketones in the blood and urine.
Diabetic acidosis (also called diabetic ketoacidosis and DKA) develops when substances called ketone bodies (which are acidic) build up during uncontrolled diabetes. Hyperchloremic acidosis is caused by the loss of too much sodium bicarbonate from the body, which can happen with severe diarrhea.
A clinical condition known as metabolic acidosis is characterised by an excess of hydrogen ions, which can come from acids other than carbonic. Ketone acids, which are created during the process of intermediate metabolism in the absence of insulin, are the source of the excessive hydrogen ions in diabetic acidosis.
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