Whenever phosphodiesterase type 5 (pde-5) inhibitors like sildenafil are prescribed, the patient should be checked for nitrate use.
The four commercially available oral PDE5 inhibitors in the United States are tadalafil (Cialis, Eli Lilly), sildenafil (Viagra, Pfizer), vardenafil (Levitra and Staxyn, Bayer/GlaxoSmithKline), and avanafil, which was only recently licensed (Stendra, Vivus).
Targeted therapies called PDE 5 inhibitors are used to treat pulmonary hypertension in patients (PH). Targeted treatments can stop the course of PH and potentially undo some of the heart and lung damage.
Furthermore, sildenafil 50 mg or sildenafil 100 mg were thought to be the most efficient drugs in the general population when compared to other PDE5 inhibitors.
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