Vertical flow type of laminar airflow workstation must be used during the course of sterile compounding a hazardous drug.
When used for sterile compounding, the outer chemotherapy gloves must be sterile. Chemotherapy gloves should be adjusted every 30 minutes unless otherwise recommended by the manufacturer's documentation and must be modified when torn, punctured, or contaminated.
Ductless Fume Hoods
Hazardous drug compounding will be needed to be conducted in a ventilated device utilizing negative pressure with redundant HEPA filters or external ventilation for non-sterile preparations. Compliant devices contain Ductless Fume Hoods, Containment Ventilated Enclosures, and Class II Biological Safety Cabinets.
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