The two features that distinguish innate lymphoid cells (ILCs) from T and B lymphocytes are:
ILCs are activated by opsonized microbes, foreign antigens, and cytokines; T and B cells are not.
T and B lymphocytes develop antigen-specific receptors; ILCs do not.
Immune cells known as innate lymphoid cells (ILCs) are expanding and mimic the phenotypes and capabilities of T cells. ILCs do not, however, express acquired antigen receptors or engage in clonal selection and proliferation when activated, in contrast to T cells, which do.
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