The non-responsive of the Kidney to the ADH signal is that conditions lead to production of a more dilute urine.
What is a dilute urine?
This means the condition when there's too much water in the urine or when the urine's concentration is weak.
Normally, the sensors in the body detect when your blood volume changes and needs more ADH and its talk to your brain and the pituitary gland releases ADH into your bloodstream.
Hence, when our ADH makes it to your kidneys, it signals them to conserve water and produce more concentrated urine.
Therefore, non-responsive of the Kidney to the ADH signal is that conditions lead to production of a more dilute urine.
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