Place the steps of endochondral ossification in order, starting with the creation of a cartilage model and ending with the presence of epiphyseal plates between the diaphysis and epiphysis.

Answer bank:

1. The diaphysis center is vascularized, and osteoblasts deposit osteoid over calcified cartilage matrix.
2. Spongy bone and the medullary cavity form in the diaphysis.
3. Spongy bone forms in the epiphysis.
4. The epiphyseal center is vascularized, and osteoblasts deposit osteoid over calcified cartilage matrix.
5. A periosteal collar develops.

A periosteal bone collar develops.
spongy bone and the medullary cavity form in the diaphysis.
The diaphysis center is vascularized and osteoblasts deposit osteoid over calcified cartilage matrix.
The epiphyseal center is vascularized and osteoblasts deposit osteoid over the calcified cartilage matrix.
The spongy bone forms in epiphysis.

Which bones grow by endochondral ossification?

Long and short bones, such as the phalanges and femur, arise from a cartilage model formed by endochondral ossification. Distinguishing between these two types of osteogenesis does not imply the existence of multiple types of bone tissue.

Endochondral ossification mainly forms in two stages: modifications of the hyaline cartilage that ends with the death of chondrocytes and invasion of osteogenic cells and their differentiation into osteoblasts in the cavities previously occupied by chondrocytes for deposition.

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