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Globular proteins are not present in the membrane.

What is the composition/structure of a cell membrane?

The fluid mosaic model, which is the presently accepted explanation for the composition of the plasma membrane, was originally put forth in 1972. The plasma membrane is a mosaic of elements, primarily phospholipids, cholesterol, and proteins, that move fluidly and freely in the plane of the membrane, according to the fluid mosaic model.

Lipids (such as phospholipids and cholesterol), proteins, and carbohydrate groups that are joined to some of the lipids and proteins make up the plasma membrane.

  • A phospholipid is a lipid composed of glycerol, two fatty acid tails, and a head group that is phosphate-linked. Phospholipid bilayers, two layers of phospholipids with their tails pointing inward, are a common component of biological membranes.
  • In the center of the membrane, next to phospholipids, is cholesterol, a different lipid made up of four fused carbon rings.
  • Membrane proteins can enter the plasma membrane only partially, cross it totally, or remain loosely connected to either the inside or outside face of the membrane.
  • The outer layer of the plasma membrane contains carbohydrate groups, which are joined to lipids or proteins to form glycolipids or glycoproteins.

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