GLUT4 is a glucose transporter protein that is detained intracellularly without insulin in different vesicles that contain proteins such as aminopeptidase.
It is the skeletal muscle-specific glucose transporter, found mainly in insulin-sensitive tissues, such as muscle and adipocytes.
The lack of insulin affects the migration of Glut-4 towards the plasmatic membrane, being stopped intracellularly in different vesicles and therefore producing a decrease in the transport of glucose into the cell.
Therefore, we can conclude that GLUT4 is a glucose transporter protein that is detained intracellularly without insulin in different vesicles that contain proteins such as aminopeptidase.
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