The notation of this karyotype is 45, X, -23. It means that they have an aneuploidy.
Aneuplodies and chromosome abnormalities
Aneuploidy is a chromosome abnormality where an individual does not have the normal number of chromosomes.
In aneuploidy, chromosomes may be laking (missing) or may be present in extra amounts.
Aneuploidies can lead to differential phenotypes (for example, Down syndrome is caused by a trisomy) and often are associated with health problems.
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