The sodium channel possesses an inactivation gate that temporarily closes after the channel is active.
In neurons, sodium channels are responsible for the ascending phase of the action potential (depolarization).
- Characteristically, this channel has two transmembrane voltage-dependent gates.
- When the membrane is depolarized to the threshold, both gates are activated, but since one of them opens rapidly while the other closes slowly, the channel remains open for less than 2-5 milliseconds.
Therefore, we can conclude that the sodium channel is responsible for the depolarization and possesses two gates which one temporarily closes after the channel is active.
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