(b) The pGoG protein is known to block the G, to S transition in the cell cycle. Explain why this prevents
miosis from happenina in he cell
(c) Before treating melanoma cells with capsaicin, researchers pretreated the cells with an inhibitor of
calcineurin. Predict the effect of this pretreatment on the ability of capsaicin to induce apoptosis by the
pathway shown in Figure 2. Provide reasoning to justify your prediction.
(d) Researchers claim that many cancers include a mutation in the gene encoding pGoG. Support the
researchers claim.