7. For some time, Adam has been experiencing fever, lethargy, muscle swelling and
tenderness, and a rash on his face, chest, and eyelids. After a number of blood tests and
treatments with various anti-inflammatory agents, the symptoms have not been
alleviated-in fact, they seem to be worsening. The strength of Adam's upper limb
muscles is measured at significantly below normal (3-) on both sides of his body. Based
on these signs and symptoms, his physician orders a muscle biopsy. Which muscle
disorder does the physician suspect? What questions could the physician ask to aid his
diagnosis, and how can the biopsy help identify the disease affecting Adam?

Question

20-10-2021
Medicine

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7. For some time, Adam has been experiencing fever, lethargy, muscle swelling and
tenderness, and a rash on his face, chest, and eyelids. After a number of blood tests and
treatments with various anti-inflammatory agents, the symptoms have not been
alleviated-in fact, they seem to be worsening. The strength of Adam's upper limb
muscles is measured at significantly below normal (3-) on both sides of his body. Based
on these signs and symptoms, his physician orders a muscle biopsy. Which muscle
disorder does the physician suspect? What questions could the physician ask to aid his
diagnosis, and how can the biopsy help identify the disease affecting Adam?

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ajeigbeibraheem ajeigbeibraheem · Answer 1 · 2021-10-25T12:43:38+02:00

For some time, Adam has been experiencing fever, lethargy, muscle swelling and tenderness, and a rash on his face, chest, and eyelids. The physician suspects that Adam might be experiencing a muscle disorder known as dermatomyositis.

Dermatomyositis is an uncommon condition that produces muscle inflammation and a rash on the skin. It is one of a series of muscular illnesses that cause inflammation and edema in the muscles. It differs from other muscle illnesses in that it also causes skin issues. Dermatomyositis refers to symptoms that affect both the muscles and the skin.

The kind of questions that the physician could ask the patient to aid his diagnosis are:

If the patient is experiencing blood when vomiting
If there is any cough
If there is joint pain

The main reason why the physician order muscle biopsy is to help unveil mononuclear leukocytes with deteriorating and dead muscle cells.

Therefore, we can conclude that these mononuclear leukocytes are located within the muscle cells and as the patient suffers from Dermatomyositis, they are being deteriorated.

Learn more about Dermatomyositis here:

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