Which of the following statements are part of Koch’s Postulates? Check all that apply.

A - The disease-causing microorganism must be present in at least half of the cases of disease.

B -The microorganism can be isolated and grown in a pure culture.

C - The microorganism from the pure culture will cause the disease in at least 80% of healthy organisms.

D - A re-isolated microorganism may evolve into a different species than the original.