Write balanced equations for all the reactions in the catabolism of glucose to two molecules of glyceraldehyde 3-phosphate (the preparatory phase of glycolysis), including the standard free-energy change for each reaction. Then write the overall or net equation for the preparatory phase of glycolysis, with the net standard free-energy change.

Respuesta :

Solution :

The balanced chemical equation are

The Catabolism of the glucose takes place in five stages :

1. Glucose + [tex]$ATP$[/tex] → glucose - [tex]$6$[/tex] - phosphate [tex]$+ ADP$[/tex]  ,  [tex]$\Delta G^0=-16.7 \ kJ/mol$[/tex]

2. Glucose - [tex]$6$[/tex] - phosphate → Fructose - [tex]$6$[/tex] - phosphate ,  [tex]$\Delta G^0=1.7 \ kJ/mol$[/tex]

3. Glucose - [tex]$6$[/tex] - phosphate + [tex]$ATP$[/tex] → [tex]$ADP$[/tex] + Fructose - [tex]$1,6- \text{biophosphate}$[/tex],  [tex]$\Delta G^0=-14.2 \ kJ/mol$[/tex]

4. Fructose - [tex]$1,6- \text{biophosphate}$[/tex]  → dihydroxyacetonephosphate + glyceraldehyde  [tex]$-3 - $[/tex] phosphate,   [tex]$\Delta G^0=23.8 \ kJ/mol$[/tex]

5. Dihydroxyacetonephosphate → glyceraldehyde  [tex]$-3 - $[/tex] phosphate , [tex]$\Delta G^0=7.5 \ kJ/mol$[/tex]

Therefore, the overall net equations

Glucose + [tex]$2ATP \rightarrow$[/tex] glyceraldehyde  [tex]$-3 - $[/tex] phosphate + [tex]$2ADP$[/tex] [tex]$\Delta G^0=2.1 \ kJ/mol$[/tex]

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