Answer:
Pyruvate - No change
NADH- No change
Intermembrane H+ Concentration- Increase
Explanation:
The concentration of both pyruvate and NADH does NOT CHANGE by Oligomycin, whereas the concentration of protons (H+) INCREASES.
Cellular respiration has three main stages: glycolysis, the Krebs cycle and oxidative phosphorylation.
Pyruvate is generated by glycolysis in the cytoplasm. This process (glycolysis) generates two molecules of pyruvate for each molecule of glucose.
Moreover, the reduced form of Nicotinamide adenine diphosphate (NADH), is produced during glycolysis and the Krebs cycle.
During oxidative phosphorylation, NADH is consumed in the electron transport chain.
NADH is used to create an electrochemical gradient by pumping protons (H+) across from the mitochondrial matrix to the inter-membrane space.
Subsequently, this electrochemical proton gradient is then used to produce ATP by an ATP synthase.
In conclusion, the concentration of both pyruvate and NADH does NOT CHANGE by Oligomycin, whereas the concentration of protons (H+) INCREASES.
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