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Answer:

The key difference between the smooth endoplasmic reticulum and rough endoplasmic reticulum is that the smooth endoplasmic reticulum does not contain ribosomes on its surface while rough endoplasmic reticulum has ribosomes on its surface.

Explanation:credit : wiki

Smooth endoplasmic reticulum consist of tubular vesicles that LACK RIBOSOMES while rough ER has ribosomes.
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