Do a punnett square for the cross shown below between a male and female, both with Hemophilia, an X-linked recessive disease. Females are represented by a circle and males by a square. Darkened shapes mean the individual has the diseas

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Answer:

Hemophilia is an X-linked recessive disease. Let the normal allele be represented as XH and the mutant allele be represented as Xh. Here,

hemophilic male = XhY

hemophilic female = XhXh

When XhY  X   XhXh the punnett square will be as follows:          

        Xh       Y

Xh  XhXh   XhY

Xh  XhXh   XhY

The entire progeny will be hemophilic since only Xh allele was passed on by both the parents.

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