Answer:The principle of teratology that this addresses is - The amount of exposure to a teratogen influences its effect.
Explanation:
Couple of factors affects the effects of teratogen ranging from the timing at which the exposure took place,the nature of teratogen and how susceptible the mother's gene is to teratogen.
When the amount of teratogen is high,it poses a risk to Karen which can be foetal malformation or miscarriage.
Low to moderate consumption of Caffeine might not be harmful to an expectant mother like Karen,but when the degree of consumption is increased according to the principle of teratology, there is an increased risk of harm to the developing foetus and even sometimes to the mother.
