Under a microscope you view a cell with an extensive smooth endoplasmic reticulum present. What could this indicate? Under a microscope you view a cell with an extensive smooth endoplasmic reticulum present. What could this indicate? a. The cell is about to divide. b. The cell is involved in detoxifying drugs. c. The cell is making a large amount of protein. d. The cell has a high energy demand.

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Answer:

The cell is involved in detoxifying drugs.

Explanation:

Apart from the exclusive function of manufacturing lipids and also in the metabolism of said lipids and associated product, the Smooth endoplasmic reticulum (so named because it is not studded with ribosomes on its surface) also assists in detoxifying materials making them more water-soluble e.g detoxifying barbiturates from drug overdose. They are abundant in the liver. They also aid in the detoxification of ethanol from excessive alcohol intake.

An extensive smooth endoplasmic reticulum could be indicative that the cell IS INVOLVED in detoxifying drugs (Option B).

  • The smooth endoplasmic reticulum (ER) is a fundamental component of the endomembrane system.

  • The endomembrane system is a group of organelles and membrane-bound structures inside eukaryotic cells, which include nuclear envelope, ER, Golgi apparatus, endosomes and lysosomes, as well as transport vesicles that stores or transports substances between different components of the system.

  • The endomembrane system is responsible for modifying, packaging, and transporting lipids and proteins inside and outside the cells.

  • The Golgi apparatus is originated from vesicular clusters that bud off the smooth ER.

  • The components of the endomembrane system function in a sequential mode:  
  1. The hydrolytic enzymes synthesized on the rough ER are packaged into transport vesicles and moved to the Golgi apparatus.
  2. The Golgi apparatus processes these enzymes.
  3. Transport vesicles from the Golgi apparatus fuse with late endosomes, converting them into lysosomes.

  • The hydrolytic enzymes contained in the lysosomes are used by detoxifying cells to digest toxic compounds (e.g., drugs) taken into the cell by endocytosis.

In conclusion, an extensive smooth ER might indicate that the cell is involved in detoxifying drugs (Option B is correct).

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