Answer:
Tay-Sachs disease results from brain lacking a specific type of lipid-digesting enzyme.
Explanation:
Tay-Sachs disease occurs when relatively large amounts of gangliosides are stored in the brain. It is the oldest lipid storage disease and is a hereditary disorder caused by deficiency of a lipid-digesting enzyme known as "hexosaminidase A", which cleaves a specific bond in the gangliosides.
Its deficiency cause accumulation of gangliosides in the lysosomes of BRAIN CELLS thereby causing degeneration of the nervous system.
