Answer: option E - It may have blinded your study.
Explanation:
A confounder is a factor, in data analysis, that causes the effects of two distinct processes to be indistinguishable/ unknown.
Of course, the confounder (factor) could have made the protective effect against heart disease a function of more than just physical activity - bringing other factors like heredity or diet history etc into consideration.
So, the confounder (factor) may have blinded your study.