Joe has been recently diagnosed with COPD. He is 57, has worked in the coal mines since he was
17, and suffers from severe dyspnea. Joe's physician prescribed
oxygen for home use at 2 L/min,
Bagonists, and corticosteroids. Joe has not responded as his physician had hoped. (Joe has had
no
change in his FEV₁.) Joe's physician has decided to initiate sustained-release theophylline and asks
you to calculate the appropriate dose for Joe, who weighs 75 kg and is 6 feet tall.
1. What dose should Joe begin with?