The LEP gene codes for an anorexigenic hormone. Interestingly, breastfeeding has been shown to alter methylation of the promoter of this gene, leading to increased LEP expression. What is likely happening in response to breastfeeding:
a. Breastfeeding increases the methylation of the promoter of the LEP gene, decreasing the spacing between nucleosomes.
b. Breastfeeding decreases the methylation of the promoter of the LEP gene, increasing the spacing between nucleosomes.
c. Breastfeeding decreases the methylation of the promoter of the LEP gene, decreasing the spacing between nucleosomes.
d. Breastfeeding increases the methylation of the promoter of the LEP gene, and the tight packing of the DNA alters binding of RNA polymerase.