α-latrotoxin, a neurotoxin in black widow spider venom, also effects acetylcholine (ach) stimulation of muscle. interestingly, organisms injected with α-latrotoxin exhibit uncontrollable muscle cramps and spasms, which after some time is then followed by complete flaccid (relaxed) muscle paralysis. considering what you know about the botulinum neurotoxin, hypothesize how α-latrotoxin may modulate exocytosis of ach.